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Complement-induced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy.

In passive Heymann nephritis (PHN) in rats, antibody (anti-Fx1A) reacts in situ with a glomerular epithelial antigen and induces complement (C)-mediated cell-independent proteinuria. To assess the role of the membrane attack complex (MAC), we determined the need for C8 in the pathogenesis of protein...

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Detalles Bibliográficos
Main Authors: Cybulsky, A V, Rennke, H G, Feintzeig, I D, Salant, D J
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC424443/
https://ncbi.nlm.nih.gov/pubmed/3514672
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