Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells.

Pharmacologic elevation of cyclic AMP (cAMP) promotes growth arrest and differentiation in a variety of transformed mammalian cells, including the HL-60 human promyelocytic leukemia cell line. However, mechanisms underlying this phenomenon are poorly understood. Because cellular oncogenes play a piv...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Slungaard, A, Confer, D L, Schubach, W H
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2437157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112987
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