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csi2p modulates microtubule dynamics and organizes the bipolar spindle for chromosome segregation

Proper chromosome segregation is of paramount importance for proper genetic inheritance. Defects in chromosome segregation can lead to aneuploidy, which is a hallmark of cancer cells. Eukaryotic chromosome segregation is accomplished by the bipolar spindle. Additional mechanisms, such as the spindle...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Costa, Judite, Fu, Chuanhai, Khare, V. Mohini, Tran, Phong T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244199/
https://ncbi.nlm.nih.gov/pubmed/25253718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1370
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