Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects

The methylation status of DNA methylation regions (DMRs) of the imprinted gene IGF2/Igf2 is associated with neural tube defects (NTDs), which are caused by a failure of the neural tube to fold and close and are the second-most common birth defect; however, the characterization of the expression leve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bai, Baoling, Zhang, Qin, Liu, Xiaozhen, Miao, Chunyue, Shangguan, Shaofang, Bao, Yihua, Guo, Jin, Wang, Li, Zhang, Ting, Li, Huili
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244157/
https://ncbi.nlm.nih.gov/pubmed/25423083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113308
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