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Design of a Highly Effective Therapeutic HPV16 E6/E7-Specific DNA Vaccine: Optimization by Different Ways of Sequence Rearrangements (Shuffling)

Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Almajhdi, Fahad N., Senger, Tilo, Amer, Haitham M., Gissmann, Lutz, Öhlschläger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244082/
https://ncbi.nlm.nih.gov/pubmed/25422946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113461
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