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Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications.
The ability of Sn(tin)-protoporphyrin to inhibit the induction of hepatic delta-aminolevulinate (ALA) synthase by allylisopropyl acetamide (AIA) was examined in the adult rat. Doses of Sn-protoporphyrin of 1, 10, and 50 mumol/kg body wt resulted in decreases in AIA-induced hepatic ALA-synthase activ...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4077989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112259 |
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