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Epigenetic changes of mesenchymal stem cells in three-dimensional (3D) spheroids

Mesenchymal stem cells (MSCs) hold profound promise in tissue repair/regeneration. However, MSCs undergo remarkable spontaneous differentiation and aging during monolayer culture expansion. In this study, we found that 2–3 days of three-dimensional (3D) spheroid culture of human MSCs (hMSCs) that ha...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Autores principales: Guo, Ling, Zhou, Ying, Wang, Shan, Wu, Yaojiong
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244016/
https://ncbi.nlm.nih.gov/pubmed/25090911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12336
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