Altered β1,6-GlcNAc branched N-glycans impair TGF-β-mediated Epithelial-to-Mesenchymal Transition through Smad signalling pathway in human lung cancer

The change of oligosaccharide structure has been revealed to be crucial for glycoproteins' biological functions and cell biological characteristics. N-acetylglucosaminy transferase V (GnT-V), a key enzyme catalysing the reaction of adding β1, 6-N-acetylglucosamine (GlcNAc) on asparagine-linked...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Li, Na, Xu, Haineng, Fan, Kun, Liu, Xijun, Qi, Jingjing, Zhao, Chao, Yin, Peng, Wang, Liying, Li, Zengxia, Zha, Xiliang
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244013/
https://ncbi.nlm.nih.gov/pubmed/24913443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12331
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