Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits

INTRODUCTION: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) represents the most common hereditary form of cerebral small vessel disease characterized by early-onset stroke and premature dementia. It is caused by mutations in the transmembrane re...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kast, Jessica, Hanecker, Patrizia, Beaufort, Nathalie, Giese, Armin, Joutel, Anne, Dichgans, Martin, Opherk, Christian, Haffner, Christof
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243959/
https://ncbi.nlm.nih.gov/pubmed/25190493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0096-8
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