Predictors and outcomes of increases in creatine phosphokinase concentrations or rhabdomyolysis risk during statin treatment

AIM: The aim was to evaluate clinical risk factors associated with myotoxicity in statin users. METHODS: This was a cohort study of patients prescribed a statin in UK primary care practices contributing to the Clinical Practice Research Datalink. Outcomes of interest were creatine phosphokinase (CPK...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: van Staa, Tjeerd P, Carr, Daniel F, O’Meara, Helen, McCann, Gerry, Pirmohamed, Munir
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Drug Safety
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243915/
https://ncbi.nlm.nih.gov/pubmed/24602118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12367
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