Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)- 2-butenal are mediated by inhibition of the STAT3 pathway

BACKGROUND AND PURPOSE: Products of Maillard reactions between aminoacids and reducing sugars are known to have anti-inflammatory properties. Here we have assessed the anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal and its possible mechanisms of action. EXPERIMENTAL APPROACH: We us...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Ban, Jung Ok, Kim, Dae Hwan, Lee, Hee Pom, Hwang, Chul Ju, Shim, Jung-Hyun, Kim, Dae Joong, Kim, Tae Myoung, Jeong, Heon-Sang, Nah, Seong Su, Chen, Hanyong, Dong, Zigang, Ham, Young Wan, Kim, Youngsoo, Han, Sang-Bae, Hong, Jin Tae
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243863/
https://ncbi.nlm.nih.gov/pubmed/24520814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12619
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