Luteolin is effective in the non-small cell lung cancer model with L858R/T790M EGF receptor mutation and erlotinib resistance

BACKGROUND AND PURPOSE: Non-small cell lung cancer (NSCLC) is one of the most commonly diagnosed malignancies in the world. Small-molecule inhibitors of the EGF receptor's tyrosine kinase domain (TKIs), including gefitinib and erlotinib, have been widely used for treating NSCLC. Unfortunately,...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Hong, Zhuan, Cao, Xiang, Li, Na, Zhang, Yizhou, Lan, Lei, Zhou, Yi, Pan, Xiaolong, Shen, Lei, Yin, Zhimin, Luo, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243859/
https://ncbi.nlm.nih.gov/pubmed/24471765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12610
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