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Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor

The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) mediates the intracellular transport of newly synthesized lysosomal enzymes containing mannose 6-phosphate on their N-linked oligosaccharides. In addition to its role in lysosome biogenesis, the CI-MPR interacts with a number of di...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Olson, Linda J, Yammani, Rama D, Dahms, Nancy M, Kim, Jung-Ja P
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424385/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15085180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600215
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