Silencing airway epithelial cell-derived hepcidin exacerbates sepsis-induced acute lung injury

INTRODUCTION: The production of antimicrobial peptides by airway epithelial cells is an important component of the innate immune response to pulmonary infection and inflammation. Hepcidin is a β-defensin-like antimicrobial peptide and acts as a principal iron regulatory hormone. Hepcidin is mostly p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Crit Care
Main Authors: Chen, Qi Xing, Song, Sheng Wen, Chen, Qing Hua, Zeng, Cong Li, Zheng, Xia, Wang, Jun Lu, Fang, Xiang Ming
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243715/
https://ncbi.nlm.nih.gov/pubmed/25096529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0470-8
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