Microfluidic continuous-flow radiosynthesis of [(18)F]FPEB suitable for human PET imaging

The synthesis of fluorine-18 labeled 3-fluoro-5-[(pyridin-3-yl)ethynyl] benzonitrile ([(18)F]FPEB) for imaging metabotropic glutamate receptor subtype type 5 (mGluR5) was achieved with a commercial continuous-flow microfluidics device. This work represents the first positron emission tomography (PET...

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Pubblicato in:Medchemcomm
Autori principali: Liang, Steven H., Yokell, Daniel L., Jackson, Raul N., Rice, Peter A., Callahan, Ronald, Johnson, Keith A., Alagille, David, Tamagnan, Gilles, Collier, Thomas Lee, Vasdev, Neil
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243709/
https://ncbi.nlm.nih.gov/pubmed/25431646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00335C
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