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Lactate oxidation at the mitochondria: a lactate-malate-aspartate shuttle at work
Lactate, the conjugate base of lactic acid occurring in aqueous biological fluids, has been derided as a “dead-end” waste product of anaerobic metabolism. Catalyzed by the near-equilibrium enzyme lactate dehydrogenase (LDH), the reduction of pyruvate to lactate is thought to serve to regenerate the...
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| Pubblicato in: | Front Neurosci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243568/ https://ncbi.nlm.nih.gov/pubmed/25505376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00366 |
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