Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model

BACKGROUND: Growth factor mediated activation of RAS-MAP-kinase and PI3-kinase-AKT pathways are critical for the pathogenesis of glioblastoma. The attenuation of PI3-kinase/AKT signaling will be effective in regulating the tumorigenic phenotypes of the glioma cells. METHODS: Glioma cells derived fro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Singh, Alok R, Joshi, Shweta, George, Elizabeth, Durden, Donald L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243316/
https://ncbi.nlm.nih.gov/pubmed/25425962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0105-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados