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Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of thrombin.

Phosphoinositide hydrolysis in platelets stimulated by thrombin is thought to be regulated by a pertussis toxin-sensitive guanine nucleotide binding protein (G protein) referred to as Gp. The present studies examine the role of Gp in platelet responses to the thromboxane A2 analogue U46619 and in th...

詳細記述

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書誌詳細
主要な著者: Brass, L F, Shaller, C C, Belmonte, E J
フォーマット: Artigo
言語:Inglês
出版事項: 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC424329/
https://ncbi.nlm.nih.gov/pubmed/3031135
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