Cell surface expression of fMet-Leu-Phe receptors on human neutrophils. Correlation to changes in the cytosolic free Ca2+ level and action of phorbol myristate acetate.

We have studied how cytosolic free Ca2+ ([Ca2+]i) changes and phorbol myristate acetate (PMA) exposure affects ligand-independent cell surface expression of fMet-Leu-Phe receptors on human neutrophils. Mere incubation primed neutrophils to double their binding of fMet-Leu-Phe. This spontaneous incre...

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Udgivet i:J Clin Invest
Main Authors: Andersson, T, Dahlgren, C, Lew, P D, Stendahl, O
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3558823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112941
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