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Visualization of genetic disease-phenotype similarities by multiple maps t-SNE with Laplacian regularization

BACKGROUND: From a phenotypic standpoint, certain types of diseases may prove to be difficult to accurately diagnose, due to specific combinations of confounding symptoms. Referred to as phenotypic overlap, these sets of disease-related symptoms suggest shared pathophysiological mechanisms. Few atte...

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Bibliographic Details
Published in:BMC Med Genomics
Main Authors: Xu, Weiwei, Jiang, Xingpeng, Hu, Xiaohua, Li, Guangrong
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243097/
https://ncbi.nlm.nih.gov/pubmed/25350393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-S2-S1
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