Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness.

Using a sensitive single isotope enzymatic assay we measured bronchoalveolar lavage (BAL) fluid histamine in asymptomatic normal (nonallergic), allergic rhinitic, and allergic asthmatic subjects. Normal subjects were found to have little or no detectable amounts of histamine in BAL fluid (11 +/- 11...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Casale, T B, Wood, D, Richerson, H B, Trapp, S, Metzger, W J, Zavala, D, Hunninghake, G W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3549781/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112937
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