Proinflammatory signaling regulates hematopoietic stem cell emergence

Hematopoietic stem cells (HSCs) underlie the production of blood and immune cells for the lifetime of an organism. In vertebrate embryos, HSCs arise from the unique transdifferentiation of hemogenic endothelium comprising the floor of the dorsal aorta during a brief developmental window. To date, th...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Espín-Palazón, Raquel, Stachura, David L., Campbell, Clyde A., García-Moreno, Diana, Cid, Natasha Del, Kim, Albert D., Candel, Sergio, Meseguer, José, Mulero, Victoriano, Traver, David
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243083/
https://ncbi.nlm.nih.gov/pubmed/25416946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.031
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