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Modelling the onset of senescence at the G1/S cell cycle checkpoint

BACKGROUND: DNA damage (single or double-strand breaks) triggers adapted cellular responses. These responses are elicited through signalling pathways, which activate cell cycle checkpoints and basically lead to three cellular fates: cycle arrest promoting DNA repair, senescence (permanent arrest) or...

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Dades bibliogràfiques
Publicat a:BMC Genomics
Autors principals: Mombach, José CM, Bugs, Cristhian A, Chaouiya, Claudine
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243082/
https://ncbi.nlm.nih.gov/pubmed/25573782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S7-S7
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