Treatment of acute myeloid leukemia cells in vitro with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.

Monoclonal antibody L4F3 reacts with most acute myeloid leukemia (AML) cells and virtually all normal granulocyte/monocyte colony-forming cells (CFU-GM). Our objective was to determine whether lysis of AML cells with L4F3 and complement allowed expression of normal myeloid progenitors. The five gluc...

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Bibliographic Details
Published in:	J Clin Invest
Main Authors:	Bernstein, I D, Singer, J W, Andrews, R G, Keating, A, Powell, J S, Bjornson, B H, Cuttner, J, Najfeld, V, Reaman, G, Raskind, W
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1987
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424297/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112932
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Treatment of acute myeloid leukemia cells in vitro with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.

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