A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation

Eukaryotic ribosome biogenesis involves ∼200 assembly factors, but how these contribute to ribosome maturation is poorly understood. Here, we identify a network of factors on the nascent 60S subunit that actively remodels preribosome structure. At its hub is Rsa4, a direct substrate of the force-gen...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Baßler, Jochen, Paternoga, Helge, Holdermann, Iris, Thoms, Matthias, Granneman, Sander, Barrio-Garcia, Clara, Nyarko, Afua, Stier, Gunter, Clark, Sarah A., Schraivogel, Daniel, Kallas, Martina, Beckmann, Roland, Tollervey, David, Barbar, Elisar, Sinning, Irmi, Hurt, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242840/
https://ncbi.nlm.nih.gov/pubmed/25404745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408111
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