Differential effects of hyperinsulinemia and hyperaminoacidemia on leucine-carbon metabolism in vivo. Evidence for distinct mechanisms in regulation of net amino acid deposition.

The effects of physiologic hyperinsulinemia and hyperaminoacidemia, alone or in combination, on leucine kinetics in vivo were studied in postabsorptive healthy subjects with primed-constant infusions of L-[4,5-3H]leucine and [1-14C]alpha-ketoisocaproate (KIC) under euglycemic conditions. Hyperinsuli...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Tessari, P, Inchiostro, S, Biolo, G, Trevisan, R, Fantin, G, Marescotti, M C, Iori, E, Tiengo, A, Crepaldi, G
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3549777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112919
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