Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion

Cytoplasmic dynein 1 (dynein) is a minus end–directed microtubule motor protein with many cellular functions, including during cell division. The role of the light intermediate chains (LICs; DYNC1LI1 and 2) within the complex is poorly understood. In this paper, we have used small interfering RNAs o...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Jones, Laura A., Villemant, Cécile, Starborg, Toby, Salter, Anna, Goddard, Georgina, Ruane, Peter, Woodman, Philip G., Papalopulu, Nancy, Woolner, Sarah, Allan, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242835/
https://ncbi.nlm.nih.gov/pubmed/25422374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408025
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