High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains.

Hybridomas obtained by in vitro stimulation with lipopolysaccharides (LPS) of BALB/c, MRL/lpr, and NZB splenocytes were selected for expression of VH7183 by hybridization using slot blotting. Northern blot analysis showed that the majority of hybrids produce a full length message complementary to th...

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Bibliographic Details
Main Authors: Bellon, B, Manheimer-Lory, A, Monestier, M, Moran, T, Dimitriu-Bona, A, Alt, F, Bona, C
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424282/
https://ncbi.nlm.nih.gov/pubmed/3558816
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