Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling

Phosphatase and tensin homolog (PTEN) loss or mutation consistently activates the phosphatidylinositol 3-kinase (PI3-K)/Akt signaling pathway, which contributes to the progression and invasiveness of prostate cancer. Furthermore, the PTEN/PI3-K/Akt and Ras/MAPK pathways cooperate to promote the epit...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Liu, Kangdong, Park, Chanmi, Chen, Hanyong, Hwang, Joonsung, Thimmegowda, N.R., Bae, Eun Young, Lee, Ki Won, Kim, Hong-Gyum, Liu, Haidan, Soung, Nak Kyun, Peng, Cong, Jang, Jae Hyuk, Kim, Kyoon Eon, Ahn, Jong Seog, Bode, Ann M., Dong, Ziming, Kim, Bo Yeon, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242796/
https://ncbi.nlm.nih.gov/pubmed/24700667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22139
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