Human transforming growth factor-alpha stimulates bone resorption in vitro.

Tumor-derived transforming growth factors (TGF) have been proposed as possible mediators of hypercalcemia in malignancy. We have studied the action of recombinant human TGF-alpha in cultured bone cells and in bone explant cultures. In clonal UMR-106 rat osteosarcoma cells, TGF-alpha and epidermal gr...

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Hauptverfasser: Stern, P H, Krieger, N S, Nissenson, R A, Williams, R D, Winkler, M E, Derynck, R, Strewler, G J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC424268/
https://ncbi.nlm.nih.gov/pubmed/3877079
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