Human transforming growth factor-alpha stimulates bone resorption in vitro.

Tumor-derived transforming growth factors (TGF) have been proposed as possible mediators of hypercalcemia in malignancy. We have studied the action of recombinant human TGF-alpha in cultured bone cells and in bone explant cultures. In clonal UMR-106 rat osteosarcoma cells, TGF-alpha and epidermal gr...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Stern, P H, Krieger, N S, Nissenson, R A, Williams, R D, Winkler, M E, Derynck, R, Strewler, G J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3877079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112202
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