Differential In Vivo Tumorigenicity of Distinct Subpopulations from a Luminal-Like Breast Cancer Xenograft

Intratumor heterogeneity caused by genetic, phenotypic or functional differences between cancer cell subpopulations is a considerable clinical challenge. Understanding subpopulation dynamics is therefore central for both optimization of existing therapy and for development of new treatment. The aim...

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Veröffentlicht in:PLoS One
Hauptverfasser: Skrbo, Nirma, Hjortland, Geir-Olav, Kristian, Alexandr, Holm, Ruth, Nord, Silje, Prasmickaite, Lina, Engebraaten, Olav, Mælandsmo, Gunhild M., Sørlie, Therese, Andersen, Kristin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242648/
https://ncbi.nlm.nih.gov/pubmed/25419568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113278
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