Affecting Pseudomonas aeruginosa Phenotypic Plasticity by Quorum Sensing Dysregulation Hampers Pathogenicity in Murine Chronic Lung Infection

In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing a critical role in pathogenesis. Multiple negative regulators modulate the timing and the extent of the QS response either in the pre-quorum or post-quorum phases of growth. This regulation likely in...

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Udgivet i:PLoS One
Main Authors: Bondí, Roslen, Messina, Marco, De Fino, Ida, Bragonzi, Alessandra, Rampioni, Giordano, Leoni, Livia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242533/
https://ncbi.nlm.nih.gov/pubmed/25420086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112105
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