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Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction

Herein, we characterize a generally applicable transformation of fatty acid epoxides by lipoxygenase (LOX) enzymes that results in the formation of a five-membered endoperoxide ring in the end product. We demonstrated this transformation using soybean LOX-1 in the metabolism of 15,16-epoxy-α-linolen...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Teder, Tarvi, Boeglin, William E., Brash, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242451/
https://ncbi.nlm.nih.gov/pubmed/25293588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054072
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