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Autologous serum improves bone formation in a primary stable silica-embedded nanohydroxyapatite bone substitute in combination with mesenchymal stem cells and rhBMP-2 in the sheep model

New therapeutic strategies are required for critical size bone defects, because the gold standard of transplanting autologous bone from an unharmed area of the body often leads to several severe side effects and disadvantages for the patient. For years, tissue engineering approaches have been seekin...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Boos, Anja M, Weigand, Annika, Deschler, Gloria, Gerber, Thomas, Arkudas, Andreas, Kneser, Ulrich, Horch, Raymund E, Beier, Justus P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242408/
https://ncbi.nlm.nih.gov/pubmed/25429218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S66867
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