Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes.

Antibodies in sera from newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients are directed to a human islet cell protein of relative molecular mass (Mr) 64,000. Since IDDM seems to develop after a prodromal period of beta-cell autoimmunity, this study has examined whether 64,000 Mr ant...

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Publicado en:J Clin Invest
Autores principales: Baekkeskov, S, Landin, M, Kristensen, J K, Srikanta, S, Bruining, G J, Mandrup-Poulsen, T, de Beaufort, C, Soeldner, J S, Eisenbarth, G, Lindgren, F
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3546382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112903
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