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Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice
The IgM-Fc receptor (FcμR) is involved in IgM homeostasis as evidenced by increased pre-immune serum IgM and natural auto-antibodies of both IgM and IgG isotypes in Fcmr-deficient C57BL/6 (B6) mice. To determine the impact of Fcmr-ablation on autoimmunity, we introduced the Fcmr null mutation onto t...
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| Publicado no: | Int Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242241/ https://ncbi.nlm.nih.gov/pubmed/24994818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxu070 |
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