Inhibition of parathyroid hormone secretion and parathyroid hormone-independent diminution of tubular calcium reabsorption by WR-2721, a unique hypocalcemic agent.

Hypocalcemia has been observed in patients receiving WR-2721 [S-,2-(3-aminopropylamino)-, ethylphosphorothioic acid]. WR-2721 is a compound that, after being dephosphorylated, provides protection of normal tissues against radio- and chemotherapy. The hypocalcemic response was accompanied by a decrea...

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Pubblicato in:	J Clin Invest
Autori principali:	Hirschel-Scholz, S, Caverzasio, J, Bonjour, J P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2997292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112178
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