Rapid Adaptation of Cardiac Ryanodine Receptors: Modulation by Mg(2+) and Phosphorylation

Channel adaptation is a fundamental feature of sarcoplasmic reticulum calcium release channels (called ryanodine receptors, RyRs). It permits successive increases in the intracellular concentration of calcium (Ca(2+)) to repeatedly but transiently activate channels. Adaptation of RyRs in the absence...

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Bibliographic Details
Published in:Science
Main Authors: Valdivia, Hector H., Kaplan, Jack H., Ellis-Davies, Graham C. R., Lederer, W. Jonathan
Format: Artigo
Language:Inglês
Published: 1995
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242209/
https://ncbi.nlm.nih.gov/pubmed/7701323
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