Monomeric (7S) IgM found in the serum of rheumatoid arthritis patients share idiotypes with pentameric (19S) monoclonal rheumatoid factors.

Serum from some seropositive (RF+) rheumatoid arthritis (RA) patients contains relatively high concentrations of monomeric (7S) IgM molecules. Seven S IgM molecules fail to bind the Fc portion of IgG, unlike 19S IgM RFs that bind aggregated IgG in classical RF assays. Some pentameric IgM RFs are mar...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Bonagura, V R, Mendez, L, Agostino, N, Pernis, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112888
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