Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase catalyzes the formation of mevalonate, an essential precursor for isoprenoid compounds in mammalian cells. Recent studies have shown that mevinolin, a competitive inhibitor of the reductase, inhibits cell proliferation and induces differentia...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Maltese, W A, Defendini, R, Green, R A, Sheridan, K M, Donley, D K
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3850904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112165
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker