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Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem.

One of the distinguishing features of the gonadotropin and thyrotropin hormone family is their heterodimeric structure, consisting of a common alpha subunit and a hormone-specific beta subunit. Subunit assembly is vital to the function of these hormones: The conformation of the heterodimer is essent...

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Autors principals: Sugahara, T, Pixley, M R, Minami, S, Perlas, E, Ben-Menahem, D, Hsueh, A J, Boime, I
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC42419/
https://ncbi.nlm.nih.gov/pubmed/7892221
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