Heterogeneity of the factor IX locus in nine hemophilia B inhibitor patients.

DNA from nine hemophilia B patients who produce anti-factor IX inhibitors (antibodies), including two brothers, was analyzed by the Southern blotting method and hybridization with factor IX cDNA, intragenomic, and 3'-flanking probes. Two inhibitor patients were shown to have total deletions of the f...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Matthews, R J, Anson, D S, Peake, I R, Bloom, A L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112880
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