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Facilitated diffusion buffers noise in gene expression

Transcription factors perform facilitated diffusion (3D diffusion in the cytosol and 1D diffusion on the DNA) when binding to their target sites to regulate gene expression. Here, we investigated the influence of this binding mechanism on the noise in gene expression. Our results showed that, for bi...

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Detalhes bibliográficos
Publicado no:Phys Rev E Stat Nonlin Soft Matter Phys
Main Authors: Schoech, Armin P., Zabet, Nicolae Radu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241468/
https://ncbi.nlm.nih.gov/pubmed/25314467
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