Evaluation of an integrated clinical workflow for targeted next-generation sequencing of low-quality tumor DNA using a 51-gene enrichment panel

BACKGROUND: Improvements in both performance and cost for next-generation sequencing (NGS) have spurred its rapid adoption for clinical applications. We designed and optimized a pan-cancer target-enrichment panel for 51 well-established oncogenes and tumor suppressors, in conjunction with a bioinfor...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Choudhary, Ashish, Mambo, Elizabeth, Sanford, Tiffany, Boedigheimer, Michael, Twomey, Brian, Califano, Joseph, Hadd, Andrew, Oliner, Kelly S, Beaudenon, Sylvie, Latham, Gary J, Adai, Alex T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241214/
https://ncbi.nlm.nih.gov/pubmed/25395014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-014-0062-0
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