Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin.

A small but consistent proportion of the von Willebrand factor (vWF) in normal plasma is composed of 189, 176, and 140 kD fragments cleaved from the 225 kD subunit. A monoclonal antibody map of vWF, based on the reactivity of individual antibodies with cyanogen bromide and tryptic fragments of known...

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Autores principales: Berkowitz, S D, Dent, J, Roberts, J, Fujimura, Y, Plow, E F, Titani, K, Ruggeri, Z M, Zimmerman, T S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC424117/
https://ncbi.nlm.nih.gov/pubmed/2433308
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