Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin.

A small but consistent proportion of the von Willebrand factor (vWF) in normal plasma is composed of 189, 176, and 140 kD fragments cleaved from the 225 kD subunit. A monoclonal antibody map of vWF, based on the reactivity of individual antibodies with cyanogen bromide and tryptic fragments of known...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Berkowitz, S D, Dent, J, Roberts, J, Fujimura, Y, Plow, E F, Titani, K, Ruggeri, Z M, Zimmerman, T S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2433308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112843
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