Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta

BACKGROUND AND PURPOSE: Dysregulated tonic tension and calcium sensitization in blood vessels has frequently been observed in many cardiovascular diseases. Despite a huge therapeutic potential, little is known about natural products targeting tonic tension and calcium sensitization. EXPERIMENTAL APP...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Lim, Kyung-Min, Kwon, Jae-Hyuk, Kim, Keunyoung, Noh, Ji-Yoon, Kang, Seojin, Park, Jung-Min, Lee, Moo-Yeol, Bae, Ok-Nam, Chung, Jin-Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241095/
https://ncbi.nlm.nih.gov/pubmed/24909118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12804
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