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Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine – a quantitative EEG study in rats
BACKGROUND AND PURPOSE: EEG studies show that 5-HT is involved in regulation of sleep–wake state and modulates cortical oscillations. Vortioxetine is a 5-HT(3), 5-HT(7), and 5-HT(1D) receptor antagonist, 5-HT(1B) partial agonist, 5-HT(1A) agonist, and 5-HT transporter inhibitor. Preclinical (animal)...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241092/ https://ncbi.nlm.nih.gov/pubmed/24846338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12782 |
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