The compound BTB06584 is an IF(1)-dependent selective inhibitor of the mitochondrial F(1)Fo-ATPase

BACKGROUND AND PURPOSE: Ischaemia compromises mitochondrial respiration. Consequently, the mitochondrial F(1)Fo-ATPsynthase reverses and acts as a proton-pumping ATPase, so maintaining the mitochondrial membrane potential (ΔΨ(m)), while accelerating ATP depletion and cell death. Here we have looked...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Ivanes, Fabrice, Faccenda, Danilo, Gatliff, Jemma, Ahmed, Ahmed A, Cocco, Stefania, Cheng, Carol Ho Ka, Allan, Emma, Russell, Claire, Duchen, Michael R, Campanella, Michelangelo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2014
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241087/
https://ncbi.nlm.nih.gov/pubmed/24641180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12638
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia