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Relationship of insulin binding and insulin-stimulated tyrosine kinase activity is altered in type II diabetes.

The insulin receptor contains an alpha subunit with insulin binding properties and a beta subunit with insulin-stimulated tyrosine kinase function. Preparations containing insulin and insulinlike growth factor I (IGF-I) receptors were obtained from solubilized human red cell membranes by affinity ch...

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Detalhes bibliográficos
Main Authors: Comi, R J, Grunberger, G, Gorden, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC424100/
https://ncbi.nlm.nih.gov/pubmed/3543053
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